基于人工智能的模型的快速发展需要创新的监视技术，这些技术可以实时以低计算成本实时运行。在机器学习中，尤其是如果我们考虑神经网络（NN）学习算法，尤其是深入学习的体系结构，则通常以监督的方式对模型进行培训。因此，在模型的部署过程中，输入和输出之间的学习关系必须保持有效。如果这种平稳性假设成立，我们可以得出结论，NN会产生准确的预测。否则，需要对模型的重建或重建。我们建议考虑NN生成的数据（称为“嵌入”）的潜在特征表示，以确定数据流开始为非平稳的时间点。确切地说，我们通过基于数据深度和归一化等级的计算应用多元控制图来监视嵌入。使用具有不同基础数据格式的各种NN评估引入方法的性能。

我们根据功能性隐藏动态地理模型（F-HDGM）的惩罚最大似然估计器（PMLE）提出了一种新型的模型选择算法。这些模型采用经典的混合效应回归结构，该结构具有嵌入式时空动力学，以模拟在功能域中观察到的地理参考数据。因此，感兴趣的参数是该域之间的函数。该算法同时选择了相关的样条基函数和回归变量，这些函数和回归变量用于对响应变量与协变量之间的固定效应关系进行建模。这样，它会自动收缩到功能系数的零部分或无关回归器的全部效果。该算法基于迭代优化，并使用自适应的绝对收缩和选择器操作员（LASSO）惩罚函数，其中未含量的F-HDGM最大likikelihood估计器获得了其中的权重。最大化的计算负担大大减少了可能性的局部二次近似。通过蒙特卡洛模拟研究，我们分析了在不同情况下算法的性能，包括回归器之间的强相关性。我们表明，在我们考虑的所有情况下，受罚的估计器的表现都优于未确定的估计器。我们将该算法应用于一个真实案例研究，其中将意大利伦巴第地区的小时二氧化氮浓度记录记录为具有多种天气和土地覆盖协变量的功能过程。

The release of ChatGPT, a language model capable of generating text that appears human-like and authentic, has gained significant attention beyond the research community. We expect that the convincing performance of ChatGPT incentivizes users to apply it to a variety of downstream tasks, including prompting the model to simplify their own medical reports. To investigate this phenomenon, we conducted an exploratory case study. In a questionnaire, we asked 15 radiologists to assess the quality of radiology reports simplified by ChatGPT. Most radiologists agreed that the simplified reports were factually correct, complete, and not potentially harmful to the patient. Nevertheless, instances of incorrect statements, missed key medical findings, and potentially harmful passages were reported. While further studies are needed, the initial insights of this study indicate a great potential in using large language models like ChatGPT to improve patient-centered care in radiology and other medical domains.

We consider a semi-supervised $k$-clustering problem where information is available on whether pairs of objects are in the same or in different clusters. This information is either available with certainty or with a limited level of confidence. We introduce the PCCC algorithm, which iteratively assigns objects to clusters while accounting for the information provided on the pairs of objects. Our algorithm can include relationships as hard constraints that are guaranteed to be satisfied or as soft constraints that can be violated subject to a penalty. This flexibility distinguishes our algorithm from the state-of-the-art in which all pairwise constraints are either considered hard, or all are considered soft. Unlike existing algorithms, our algorithm scales to large-scale instances with up to 60,000 objects, 100 clusters, and millions of cannot-link constraints (which are the most challenging constraints to incorporate). We compare the PCCC algorithm with state-of-the-art approaches in an extensive computational study. Even though the PCCC algorithm is more general than the state-of-the-art approaches in its applicability, it outperforms the state-of-the-art approaches on instances with all hard constraints or all soft constraints both in terms of running time and various metrics of solution quality. The source code of the PCCC algorithm is publicly available on GitHub.

Linear partial differential equations (PDEs) are an important, widely applied class of mechanistic models, describing physical processes such as heat transfer, electromagnetism, and wave propagation. In practice, specialized numerical methods based on discretization are used to solve PDEs. They generally use an estimate of the unknown model parameters and, if available, physical measurements for initialization. Such solvers are often embedded into larger scientific models or analyses with a downstream application such that error quantification plays a key role. However, by entirely ignoring parameter and measurement uncertainty, classical PDE solvers may fail to produce consistent estimates of their inherent approximation error. In this work, we approach this problem in a principled fashion by interpreting solving linear PDEs as physics-informed Gaussian process (GP) regression. Our framework is based on a key generalization of a widely-applied theorem for conditioning GPs on a finite number of direct observations to observations made via an arbitrary bounded linear operator. Crucially, this probabilistic viewpoint allows to (1) quantify the inherent discretization error; (2) propagate uncertainty about the model parameters to the solution; and (3) condition on noisy measurements. Demonstrating the strength of this formulation, we prove that it strictly generalizes methods of weighted residuals, a central class of PDE solvers including collocation, finite volume, pseudospectral, and (generalized) Galerkin methods such as finite element and spectral methods. This class can thus be directly equipped with a structured error estimate and the capability to incorporate uncertain model parameters and observations. In summary, our results enable the seamless integration of mechanistic models as modular building blocks into probabilistic models.

With more and more data being collected, data-driven modeling methods have been gaining in popularity in recent years. While physically sound, classical gray-box models are often cumbersome to identify and scale, and their accuracy might be hindered by their limited expressiveness. On the other hand, classical black-box methods, typically relying on Neural Networks (NNs) nowadays, often achieve impressive performance, even at scale, by deriving statistical patterns from data. However, they remain completely oblivious to the underlying physical laws, which may lead to potentially catastrophic failures if decisions for real-world physical systems are based on them. Physically Consistent Neural Networks (PCNNs) were recently developed to address these aforementioned issues, ensuring physical consistency while still leveraging NNs to attain state-of-the-art accuracy. In this work, we scale PCNNs to model building temperature dynamics and propose a thorough comparison with classical gray-box and black-box methods. More precisely, we design three distinct PCNN extensions, thereby exemplifying the modularity and flexibility of the architecture, and formally prove their physical consistency. In the presented case study, PCNNs are shown to achieve state-of-the-art accuracy, even outperforming classical NN-based models despite their constrained structure. Our investigations furthermore provide a clear illustration of NNs achieving seemingly good performance while remaining completely physics-agnostic, which can be misleading in practice. While this performance comes at the cost of computational complexity, PCNNs on the other hand show accuracy improvements of 17-35% compared to all other physically consistent methods, paving the way for scalable physically consistent models with state-of-the-art performance.

Neuromorphic systems require user-friendly software to support the design and optimization of experiments. In this work, we address this need by presenting our development of a machine learning-based modeling framework for the BrainScaleS-2 neuromorphic system. This work represents an improvement over previous efforts, which either focused on the matrix-multiplication mode of BrainScaleS-2 or lacked full automation. Our framework, called hxtorch.snn, enables the hardware-in-the-loop training of spiking neural networks within PyTorch, including support for auto differentiation in a fully-automated hardware experiment workflow. In addition, hxtorch.snn facilitates seamless transitions between emulating on hardware and simulating in software. We demonstrate the capabilities of hxtorch.snn on a classification task using the Yin-Yang dataset employing a gradient-based approach with surrogate gradients and densely sampled membrane observations from the BrainScaleS-2 hardware system.

Objective: Imbalances of the electrolyte concentration levels in the body can lead to catastrophic consequences, but accurate and accessible measurements could improve patient outcomes. While blood tests provide accurate measurements, they are invasive and the laboratory analysis can be slow or inaccessible. In contrast, an electrocardiogram (ECG) is a widely adopted tool which is quick and simple to acquire. However, the problem of estimating continuous electrolyte concentrations directly from ECGs is not well-studied. We therefore investigate if regression methods can be used for accurate ECG-based prediction of electrolyte concentrations. Methods: We explore the use of deep neural networks (DNNs) for this task. We analyze the regression performance across four electrolytes, utilizing a novel dataset containing over 290000 ECGs. For improved understanding, we also study the full spectrum from continuous predictions to binary classification of extreme concentration levels. To enhance clinical usefulness, we finally extend to a probabilistic regression approach and evaluate different uncertainty estimates. Results: We find that the performance varies significantly between different electrolytes, which is clinically justified in the interplay of electrolytes and their manifestation in the ECG. We also compare the regression accuracy with that of traditional machine learning models, demonstrating superior performance of DNNs. Conclusion: Discretization can lead to good classification performance, but does not help solve the original problem of predicting continuous concentration levels. While probabilistic regression demonstrates potential practical usefulness, the uncertainty estimates are not particularly well-calibrated. Significance: Our study is a first step towards accurate and reliable ECG-based prediction of electrolyte concentration levels.

The evolution of wireless communications into 6G and beyond is expected to rely on new machine learning (ML)-based capabilities. These can enable proactive decisions and actions from wireless-network components to sustain quality-of-service (QoS) and user experience. Moreover, new use cases in the area of vehicular and industrial communications will emerge. Specifically in the area of vehicle communication, vehicle-to-everything (V2X) schemes will benefit strongly from such advances. With this in mind, we have conducted a detailed measurement campaign with the purpose of enabling a plethora of diverse ML-based studies. The resulting datasets offer GPS-located wireless measurements across diverse urban environments for both cellular (with two different operators) and sidelink radio access technologies, thus enabling a variety of different studies towards V2X. The datasets are labeled and sampled with a high time resolution. Furthermore, we make the data publicly available with all the necessary information to support the on-boarding of new researchers. We provide an initial analysis of the data showing some of the challenges that ML needs to overcome and the features that ML can leverage, as well as some hints at potential research studies.

Biometrics are one of the most privacy-sensitive data. Ubiquitous authentication systems with a focus on privacy favor decentralized approaches as they reduce potential attack vectors, both on a technical and organizational level. The gold standard is to let the user be in control of where their own data is stored, which consequently leads to a high variety of devices used. Moreover, in comparison with a centralized system, designs with higher end-user freedom often incur additional network overhead. Therefore, when using face recognition for biometric authentication, an efficient way to compare faces is important in practical deployments, because it reduces both network and hardware requirements that are essential to encourage device diversity. This paper proposes an efficient way to aggregate embeddings used for face recognition based on an extensive analysis on different datasets and the use of different aggregation strategies. As part of this analysis, a new dataset has been collected, which is available for research purposes. Our proposed method supports the construction of massively scalable, decentralized face recognition systems with a focus on both privacy and long-term usability.